Recombinant Mouse Pclaf Protein, Myc/DDK-tagged

• Cat.No.: Pclaf-4713M
• Product Overview: Purified recombinant protein of mouse full-length PCNA clamp associated factor (Pclaf), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. Following DNA damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, facilitating the bypass of replication-fork-blocking lesions. Also acts as a regulator of centrosome number.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 12 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Pclaf PCNA clamp associated factor [ Mus musculus (house mouse) ]
• Official Symbol: Pclaf
• Synonyms: Pclaf; PCNA clamp associated factor; Paf; PAF15; p15(P; Ns5apt9; Ns5atp9; AA409629; p15(PAF); mKIAA0101; 2810417H13Rik; PCNA-associated factor; HCV NS5A-transactivated protein 9 homolog; PCNA-associated factor of 15 kDa; p15PAF
• Gene ID: 68026
• mRNA Refseq: NM_026515
• Protein Refseq: NP_080791
• UniProt ID: Q9CQX4