Recombinant Human PCLAF Protein (1-111 aa), GST-tagged

• Cat.No.: PCLAF-598H
• Product Overview: Recombinant Human PCLAF Protein (1-111 aa) is produced by E. coli expression system. This protein is fused with a GST tag at the N-terminal. Protein Description: Full Length.

Specification

• Description: PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. Following DNA damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, facilitating the bypass of replication-fork-blocking lesions. Also acts as a regulator of centrosome number.
• Source: E. coli
• Species: Human
• Tag: GST
• Form: Tris-based buffer, 50% glycerol
• Molecular Mass: 39.0 kDa
• Protein length: 1-111 aa
• AA Sequence: MVRTKADSVPGTYRKVVAARAPRKV LGSSTSATNSTSVSSRKAENKYAGG NPVCVRPTPKWQKGIGEFFRLSPKD SEKENQIPEEAGSSGLGKAKRKACP LQPDHTNDEKE
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA with concentration instruction is sent along with the products.

Gene Information

• Gene Name: PCLAF PCNA clamp associated factor [ Homo sapiens (human) ]
• Official Symbol: PCLAF
• Synonyms: L5; PAF; OEATC; PAF15; OEATC1; p15PAF; NS5ATP9; OEATC-1; p15/PAF; KIAA0101; p15(PAF)
• Gene ID: 9768
• UniProt ID: Q15004