| Cat.No. : |
PCSK5-711M |
| Product Overview : |
Recombinant Mouse PCSK5 Protein (117-452 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Protein Description: Full Length of Mature Protein. |
| Description : |
Plays an essential role in pregnancy establishment by proteolytic activation of a number of important factors such as BMP2, CALD1 and alpha-integrins. Likely to represent a widespread endoprotease activity within the constitutive and regulated secretory pathway. Capable of cleavage at the RX(K/R)R consensus motif. May be responsible for the maturation of gastrointestinal peptides. May be involved in the cellular proliferation of adrenal cortex via the activation of growth factors. |
| Source : |
E. coli |
| Species : |
Mouse |
| Tag : |
His-SUMO |
| Form : |
Tris-based buffer, 50% glycerol |
| Molecular Mass : |
52.7 kDa |
| Protein length : |
117-452 aa |
| AA Sequence : |
DYDLSHAQST YFNDPKWPSM WYMHCSDNTH PCQSDMNIEG AWKRGYTGKN IVVTILDDGI ERTHPDLMQN YDALASCDVN GNDLDPMPRY DASNENKHGT RCAGEVAATA NNSHCTVGIA FNAKIGGVRM LDGDVTDMVE AKSVSYNPQH VHIYSASWGP DDDGKTVDGP APLTRQAFEN GVRMGRRGLG SVFVWASGNG GRSKDHCSCD GYTNSIYTIS ISSTAESGKK PWYLEECSST LATTYSSGES YDKKIITTDL RQRCTDNHTG TSASAPMAAG IIALALEANP FLTWRDVQHV IVRTSRAGHL NANDWKTNAA GFKVSHLYGF GLMDAE |
| Purity : |
> 90% as determined by SDS-PAGE. |
| Notes : |
Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
| Storage : |
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
| Concentration : |
A hardcopy of COA with concentration instruction is sent along with the products. |
| Figure : |
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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