Recombinant Mouse Pdcl3 Protein, Myc/DDK-tagged

• Cat.No.: Pdcl3-4738M
• Product Overview: Purified recombinant protein of mouse full-length phosducin-like 3 (Pdcl3), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Acts as a chaperone for the angiogenic VEGF receptor KDR/VEGFR2, increasing its abundance by inhibiting its ubiquitination and degradation Inhibits the folding activity of the chaperonin-containing T-complex (CCT) which leads to inhibition of cytoskeletal actin folding. Acts as a chaperone during heat shock alongside HSP90 and HSP40/70 chaperone complexes. Modulates the activation of caspases during apoptosis.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 27.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Pdcl3 phosducin-like 3 [ Mus musculus (house mouse) ]
• Official Symbol: Pdcl3
• Synonyms: PDCL3; phosducin-like 3; phosducin-like protein 3; VIAF-1; IAP-associated factor VIAF1; viral IAP-associated factor 1; Viaf1; C80025; 1110061A19Rik
• Gene ID: 68833
• mRNA Refseq: NM_026850
• Protein Refseq: NP_081126
• UniProt ID: Q8BVF2