Recombinant Mouse Pde12 Protein, Myc/DDK-tagged
| Cat.No. : | Pde12-4741M |
| Product Overview : | Purified recombinant protein of mouse full-length phosphodiesterase 12 (Pde12), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
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| Description : | Enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. Degrades triphosphorylated 2-5A to produce AMP and ATP. Also cleaves 3',5'-phosphodiester bond of oligoadenylates. Plays a role as a negative regulator of the 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs). Suppression of this enzyme increases cellular 2-5A levels and decreases viral replication in cultured small-airway epithelial cells. |
| Source : | HEK293T |
| Species : | Mouse |
| Tag : | Myc/DDK |
| Molecular Mass : | 67.5 kDa |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Storage : | Store at -80 centigrade after receiving vials. |
| Concentration : | >50 μg/mL as determined by microplate BCA method |
| Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
| Gene Name : | Pde12 phosphodiesterase 12 [ Mus musculus (house mouse) ] |
| Official Symbol : | Pde12 |
| Synonyms : | PDE12; phosphodiesterase 12; 2,5-phosphodiesterase 12; 2-PDE; 2-phosphodiesterase; E430028B21Rik |
| Gene ID : | 211948 |
| mRNA Refseq : | NM_178668 |
| Protein Refseq : | NP_848783 |
| UniProt ID : | Q3TIU4 |
Products Types
| ◆ Recombinant Protein | ||
| PDE12-744H | Recombinant Human PDE12 Protein, MYC/DDK-tagged | +Inquiry |
| Pde12-305M | Recombinant Mouse Pde12 Protein, His-tagged | +Inquiry |
| PDE12-6582M | Recombinant Mouse PDE12 Protein, His (Fc)-Avi-tagged | +Inquiry |
| PDE12-3162R | Recombinant Rhesus Macaque PDE12 Protein, His (Fc)-Avi-tagged | +Inquiry |
| PDE12-3813H | Recombinant Human PDE12 Protein, His (Fc)-Avi-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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