Recombinant Mouse Pde5a Protein, Myc/DDK-tagged

• Cat.No.: Pde5a-4748M
• Product Overview: Purified recombinant protein of mouse full-length phosphodiesterase 5A, cGMP-specific (Pde5a), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP. Specifically regulates nitric-oxide-generated cGMP.
• Molecular Mass: 98.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Pde5a phosphodiesterase 5A, cGMP-specific [ Mus musculus (house mouse) ]
• Official Symbol: Pde5a
• Synonyms: PDE5A; phosphodiesterase 5A, cGMP-specific; cGMP-specific 3,5-cyclic phosphodiesterase; CGB-PDE; cGMP-binding cGMP-specific phosphodiesterase; cGMP-binding/cGMP-specific phosphodiesterase; Cn5n; Pde5; Cgbpde; Pde5a1
• Gene ID: 242202
• mRNA Refseq: NM_153422
• Protein Refseq: NP_700471
• UniProt ID: Q8CG03