Recombinant Mouse Pde6d Protein, Myc/DDK-tagged

• Cat.No.: Pde6d-4749M
• Product Overview: Purified recombinant protein of mouse full-length phosphodiesterase 6D, cGMP-specific, rod, delta (Pde6d), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Promotes the release of prenylated target proteins from cellular membranes Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI) Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 17.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Pde6d phosphodiesterase 6D, cGMP-specific, rod, delta [ Mus musculus (house mouse) ]
• Official Symbol: Pde6d
• Synonyms: PDE6D; phosphodiesterase 6D, cGMP-specific, rod, delta; retinal rod rhodopsin-sensitive cGMP 3,5-cyclic phosphodiesterase subunit delta; GMP-PDE delta; AI841218; PrBP/delta
• Gene ID: 18582
• mRNA Refseq: NM_008801
• Protein Refseq: NP_032827
• UniProt ID: O55057