Recombinant Mouse Pde9a Protein, Myc/DDK-tagged

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Recombinant Mouse Pde9a Protein, Myc/DDK-tagged

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Cat.No. : Pde9a-4753M
Product Overview : Purified recombinant protein of mouse full-length phosphodiesterase 9A (Pde9a), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
Description : Specifically hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. Highly specific: compared to other members of the cyclic nucleotide phosphodiesterase family, has the highest affinity and selectivity for cGMP. Specifically regulates natriuretic-peptide-dependent cGMP signaling in heart, acting as a regulator of cardiac hypertrophy in myocytes and muscle. Does not regulate nitric oxide-dependent cGMP in heart Additional experiments are required to confirm whether its ability to hydrolyze natriuretic-peptide-dependent cGMP is specific to heart or is a general feature of the protein (Probable). In brain, involved in cognitive function, such as learning and long-term memory.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 61.6 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Pde9a phosphodiesterase 9A [ Mus musculus (house mouse) ]
Official Symbol : Pde9a
Synonyms : PDE9A; phosphodiesterase 9A; high affinity cGMP-specific 3,5-cyclic phosphodiesterase 9A; PDE9A1
Gene ID : 18585
mRNA Refseq : NM_008804
Protein Refseq : NP_032830
UniProt ID : O70628
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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