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Active Recombinant Mouse PDPN protein, His-tagged

Cat.No. : PDPN-855M
Product Overview : Recombinant Mouse PDPN protein(NP_034459.2)(Met1-Lys133), fused with His tag, was expressed in Insect Cells.
  • Specification
  • Gene Information
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Source : Insect Cells
Species : Mouse
Tag : His
Form : Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 7.4, 10% glyPlease contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Bio-activity : Measured by its ability to bind recombinant CLEC1B-His/Biotin in a functional ELISA.
Molecular Mass : The recombinant mouse PDPN(aa 1-133) consists of 121 amino acids and has a calculated molecular mass of 13 kDa. It migrates as an approximately 25 KDa band in SDS-PAGE under reducing conditions.
Proteinlength : Met1-Lys133
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method
Purity : > 92 % as determined by SDS-PAGE
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : Pdpn podoplanin [ Mus musculus ]
Official Symbol : PDPN
Synonyms : PDPN; podoplanin; aggrus; PA2.26 antigen; glycoprotein 38; transmembrane glycoprotein E11; T1a; Gp38; OTS-8; T1alpha; RANDAM-2; T1-alpha;
Gene ID : 14726
mRNA Refseq : NM_010329
Protein Refseq : NP_034459

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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What role does PDPN play in cancer progression, particularly in terms of tumor cell migration and metastasis? 07/24/2022

PDPN facilitates cancer progression by promoting tumor cell migration and enhancing metastatic potential.

How does PDPN contribute to the development and maintenance of lymphatic vessels? 05/20/2022

PDPN is crucial for lymphatic vessel development and maintenance, aiding in lymphatic system function.

How does the alteration of PDPN expression impact the pathogenesis of diseases like fibrosis and lymphedema? 03/17/2021

Changes in PDPN expression contribute to fibrosis and lymphedema pathogenesis, affecting tissue structure and fluid balance.

What is the significance of PDPN in the formation and stability of blood-lymphatic vessel junctions? 07/31/2020

PDPN is significant in forming and stabilizing blood-lymphatic vessel junctions, ensuring proper vascular function.

What are the mechanisms by which PDPN modulates platelet aggregation and blood coagulation? 04/14/2020

PDPN affects platelet aggregation and blood coagulation, playing a role in thrombosis and hemostasis.

How does PDPN expression affect the interaction between tumor cells and the immune system? 02/15/2019

PDPN expression on tumor cells alters their interaction with the immune system, impacting immune evasion.

How does PDPN influence wound healing and tissue regeneration processes? 04/10/2018

PDPN plays a role in wound healing and tissue regeneration, influencing cell migration and tissue repair.

Customer Reviews (3)

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Reviews
01/31/2021

    Swift protein expression optimization support; greatly appreciated.

    08/19/2019

      Accurate protein structural characterization; indispensable for our research.

      12/19/2018

        Reliable mass spectrometry analysis; pivotal for proteomics experiments.

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