Recombinant Mouse Phlda3 protein, MYC/DDK-tagged

• Cat.No.: PHLDA3-12745M
• Product Overview: Recombinant Mouse Phlda3 protein (full-length) fused with MYC/DDK tag at the C-terminus was expressed in HEK293T.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its direct transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May act as a tumor suppressor.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 13.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Concentration: >50 μg/mL as determined by microplate BCA method.

Gene Information

• Gene Name: Phlda3
• Official Symbol: Phlda3
• Synonyms: Tih1
• Gene ID: 27280
• mRNA Refseq: NM_013750.2
• Protein Refseq: NP_038778.1
• UniProt ID: Q9WV95