Recombinant Mouse Pik3ap1 Protein, Myc/DDK-tagged

• Cat.No.: Pik3ap1-4861M
• Product Overview: Purified recombinant protein of mouse full-length phosphoinositide-3-kinase adaptor protein 1 (Pik3ap1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Signaling adapter that contributes to B-cell development by linking B-cell receptor (BCR) signaling to the phosphoinositide 3-kinase (PI3K)-Akt signaling pathway. Has a complementary role to the BCR coreceptor CD19, coupling BCR and PI3K activation by providing a docking site for the PI3K subunit PIK3R1. Alternatively, links Toll-like receptor (TLR) signaling to PI3K activation, a process preventing excessive inflammatory cytokine production. Also involved in the activation of PI3K in natural killer cells. May be involved in the survival of mature B-cells via activation of REL.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 91.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 [ Mus musculus (house mouse) ]
• Official Symbol: Pik3ap1
• Synonyms: PIK3AP1; phosphoinositide-3-kinase adaptor protein 1; phosphoinositide 3-kinase adapter protein 1; B cell phosphoinositide 3-kinase adaptor; B-cell adapter for phosphoinositide 3-kinase; B-cell phosphoinositide 3-kinase adapter protein 1; BCAP; 1810044J04Rik
• Gene ID: 83490
• mRNA Refseq: NM_031376
• Protein Refseq: NP_113553
• UniProt ID: Q9EQ32