Recombinant Mouse Pik3r1 Protein, Myc/DDK-tagged
Cat.No. : | Pik3r1-4865M |
Product Overview : | Purified recombinant protein of mouse full-length phosphoinositide-3-kinase regulatory subunit 1 (Pik3r1), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling. Modulates the cellular response to ER stress by promoting nuclear translocation of XBP1 isoform 2 in a ER stress- and/or insulin-dependent manner during metabolic overloading in the liver and hence plays a role in glucose tolerance improvement |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 83.5 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 [ Mus musculus (house mouse) ] |
Official Symbol : | Pik3r1 |
Synonyms : | PIK3R1; phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha); phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase subunit p85-alpha; PI3K regulatory subunit alpha; PI3-kinase regulatory subunit alpha; ptdIns-3-kinase regulatory subunit alpha; ptdIns-3-kinase regulatory subunit p85-alpha; phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3K; AA414921; p50alpha; p55alpha; p85alpha; C530050K14 |
Gene ID : | 18708 |
mRNA Refseq : | NM_001077495 |
Protein Refseq : | NP_001070963 |
UniProt ID : | P26450 |
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PIK3R1-4934H | Recombinant Human PIK3R1 Protein, His-tagged | +Inquiry |
PIK3R1-316H | Recombinant Human PIK3R2 protein, His/MBP-tagged | +Inquiry |
PIK3R1&Pik3ca-155H | Active Recombinant Human PIK3CA and Mouse Pik3ca protein, His-tagged | +Inquiry |
◆ Lysates | ||
PIK3R1-3185HCL | Recombinant Human PIK3R1 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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