Recombinant Mouse Pld3 Protein, Myc/DDK-tagged

• Cat.No.: Pld3-4922M
• Product Overview: Purified recombinant protein of mouse full-length phospholipase D family, member 3 (Pld3), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: 5'->3' DNA exonuclease which digests single-stranded DNA (ssDNA) Regulates inflammatory cytokine responses via the degradation of nucleic acids, by reducing the concentration of ssDNA able to stimulate TLR9, a nucleotide-sensing receptor in collaboration with PLD4 May be important in myotube formation. Plays a role in lysosomal homeostasis. Involved in the regulation of endosomal protein sorting.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 54.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Pld3 phospholipase D family, member 3 [ Mus musculus (house mouse) ]
• Official Symbol: Pld3
• Synonyms: PLD3; phospholipase D family, member 3; phospholipase D3; PLD 3; choline phosphatase 3; schwannoma-associated protein 9; phosphatidylcholine-hydrolyzing phospholipase D3; Sam-9
• Gene ID: 18807
• mRNA Refseq: NM_011116
• Protein Refseq: NP_035246
• UniProt ID: O35405