Recombinant Mouse PLK4 Protein
Cat.No. : | PLK4-12980M |
Product Overview : | Recombinant Mouse PLK4 full length or partial length protein was expressed. |
- Specification
- Gene Information
- Related Products
Source : | Mammalian Cells |
Species : | Mouse |
Tag : | His |
Form : | Liquid or lyophilized powder |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | >80% |
Notes : | This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. |
Storage : | Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC. |
Storage Buffer : | PBS buffer |
Gene Name : | Plk4 polo-like kinase 4 [ Mus musculus ] |
Official Symbol : | PLK4 |
Gene ID : | 20873 |
mRNA Refseq : | NM_011495.2 |
Protein Refseq : | NP_035625.2 |
MIM : | |
UniProt ID : | Q64702 |
Products Types
◆ Recombinant Protein | ||
PLK4-1166H | Recombinant Human PLK4 Protein (G581-G808), Tag Free | +Inquiry |
PLK4-01H | Recombinant Human PLK4 (G95L) Protein, GST-tagged | +Inquiry |
PLK4-1167H | Recombinant Human PLK4 Protein (G581-G808), His tagged | +Inquiry |
PLK4-39H | Recombinant Active Human PLK4 (G95L) Mutant Protein, GST-tagged | +Inquiry |
PLK4-6854M | Recombinant Mouse PLK4 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
PLK4-3102HCL | Recombinant Human PLK4 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionThere is an interaction between PLK4 protein and other proteins. For example, it interacts with certain proteins on spindle fibers to regulate chromosome segregation, and with other proteins in signal transduction pathways to regulate cell proliferation and differentiation.
PLK4 protein is mainly responsible for regulating the process of chromosome segregation and cytoplasmic division in cell division. It is associated with the assembly and function of spindle fibers, affecting the accuracy of chromosome segregation and cell division.
Certain biomolecules can be used as molecular markers of PLK4 protein, such as mRNA or protein of PLK4 protein detected in biological samples such as blood and urine. These markers can be used for early diagnosis of disease, prognostic judgment, or monitoring of treatment efficacy.
Therapeutics targeting the PLK4 protein are still in the early stages of research. A number of small molecule inhibitors and antibody drugs have been developed and initially evaluated in laboratories and clinical trials. However, further research and clinical validation of these treatments are needed to determine their safety and efficacy.
Therapeutic strategies for PLK4 protein include inhibition of its activity, regulation of its expression, and gene therapy. For example, the development of small molecule inhibitors or antibody drugs against the PLK4 protein to inhibit its aberrant activity in tumors, or the regulation of PLK4 protein expression through gene knockout or overexpression techniques.
Studies have shown that the abnormal expression of PLK4 protein is associated with the occurrence of a variety of tumors, including but not limited to brain cancer, lung cancer, breast cancer, pancreatic cancer, etc. It may be related to aspects such as proliferation, metastasis, and drug resistance of tumor cells.
Customer Reviews (3)
Write a reviewWith PLK4, the sensitivity of the experiment was significantly improved.
Strong anti-pollution ability, not easy to pollute, to ensure the accuracy of the experiment.
The method is very simple, and it is easy to obtain accurate experimental results.
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