Recombinant Full Length Human PLXNA1 Protein, C-Flag-tagged

• Cat.No.: PLXNA1-1329HFL
• Product Overview: Recombinant Full Length Human PLXNA1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: Predicted to enable semaphorin receptor activity. Predicted to be involved in several processes, including generation of neurons; regulation of GTPase activity; and regulation of cell shape. Predicted to act upstream of or within dichotomous subdivision of terminal units involved in salivary gland branching; neuron projection morphogenesis; and regulation of smooth muscle cell migration. Located in cytosol and nucleoplasm.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 210.9 kDa
• AA Sequence: MPLPPRSLQVLLLLLLLLLLLPGMW AEAGLPRAGGGSQPPFRTFSASDWG LTHLVVHEQTGEVYVGAVNR IYKLSGNLTLLRAHVTGPVEDNEKC YPPPSVQSCPHGLGSTDNVNKLLLL DYAANRLLACGSASQGICQF LRLDDLFKLGEPHHRKEHYLSSVQE AGSMAGVLIAGPPGQGQAKLFVGTP IDGKSEYFPTLSSRRLMANE EDADMFGFVYQDEFVSSQLKIPSDT LSKFPAFDIYYVYSFRSEQFVYYLT LQLDTQLTSPDAAGEHFFTS KIVRLCVDDPKFYSYVEFPIGCEQA GVEYRLVQDAYLSRPGRALAHQLGL AEDEDVLFTVFAQGQKNRVK PPKESALCLFTLRAIKEKIKERIQS CYRGEGKLSLPWLLNKELGCINSPL QIDDDFCGQDFNQPLGGTVT IEGTPLFVDKDDGLTAVAAYDYRGR TVVFAGTRSGRIRKILVDLSNPGGR PALAYESVVAQEGSPILRDL VLSPNHQYLYAMTEKQVTRVPVESC VQYTSCELCLGSRDPHCGWCVLHSI CSRRDACERADEPQRFAADL LQCVQLTVQPRNVSVTMSQVPLVLQ AWNVPDLSAGVNCSFEDFTESESVL EDGRIHCRSPSAREVAPITR GQGDQRVVKLYLKSKETGKKFASVD FVFYNCSVHQSCLSCVNGSFPCHWC KYRHVCTHNVADCAFLEGRV NVSEDCPQILPSTQIYVPVGVVKPI TLAARNLPQPQSGQRGYECLFHIPG SPARVTALRFNSSSLQCQNS SYSYEGNDVSDLPVNLSVVWNGNFV IDNPQNIQAHLYKCPALRESCGLCL KADPRFECGWCVAERRCSLR HHCAADTPASWMHARHGSSRCTDPK ILKLSPETGPRQGGTRLTITGENLG LRFEDVRLGVRVGKVLCSPV ESEYISAEQIVCEIGDASSVRAHDA LVEVCVRDCSPHYRALSPKRFTFVT PTFYRVSPSRGPLSGGTWIG IEGSHLNAGSDVAVSVGGRPCSFSW RNSREIRCLTPPGQSPGSAPIIINI NRAQLTNPEVKYNYTEDPTI LRIDPEWSINSGGTLLTVTGTNLAT VREPRIRAKYGGIERENGCLVYNDT TMVCRAPSVANPVRSPPELG ERPDELGFVMDNVRSLLVLNSTSFL YYPDPVLEPLSPTGLLELKPSSPLI LKGRNLLPPAPGNSRLNYTV LIGSTPCTLTVSETQLLCEAPNLTG QHKVTVRAGGFEFSPGTLQVYSDSL LTLPAIVGIGGGGGLLLLVI VAVLIAYKRKSRDADRTLKRLQLQM DNLESRVALECKEAFAELQTDIHEL TNDLDGAGIPFLDYRTYAMR VLFPGIEDHPVLKEMEVQANVEKSL TLFGQLLTKKHFLLTFIRTLEAQRS FSMRDRGNVASLIMTALQGE MEYATGVLKQLLSDLIEKNLESKNH PKLLLRRTESVAEKMLTNWFTFLLY KFLKECAGEPLFMLYCAIKQ QMEKGPIDAITGEARYSLSEDKLIR QQIDYKTLTLNCVNPENENAPEVPV KGLDCDTVTQAKEKLLDAAY KGVPYSQRPKAADMDLEWRQGRMAR IILQDEDVTTKIDNDWKRLNTLAHY QVTDGSSVALVPKQTSAYNI SNSSTFTKSLSRYESMLRTASSPDS LRSRTPMITPDLESGTKLWHLVKNH DHLDQREGDRGSKMVSEIYL TRLLATKGTLQKFVDDLFETIFSTA HRGSALPLAIKYMFDFLDEQADKHQ IHDADVRHTWKSNCLPLRFW VNVIKNPQFVFDIHKNSITDACLSV VAQTFMDSCSTSEHKLGKDSPSNKL LYAKDIPNYKSWVERYYADI AKMPAISDQDMSAYLAEQSRLHLSQ FNSMSALHEIYSYITKYKDEILAAL EKDEQARRQRLRSKLEQVVD
  TMALSSTRTRPLEQKLISEEDLAAN DILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Axon guidance

Gene Information

• Gene Name: PLXNA1 plexin A1 [ Homo sapiens (human) ]
• Official Symbol: PLXNA1
• Synonyms: NOV; NOVP; PLXN1; DWOPNED; PLEXIN-A1
• Gene ID: 5361
• mRNA Refseq: NM_032242.4
• Protein Refseq: NP_115618.3
• MIM: 601055
• UniProt ID: Q9UIW2