Recombinant Mouse Pnpla2 Protein, Myc/DDK-tagged

• Cat.No.: Pnpla2-4972M
• Product Overview: Purified recombinant protein of mouse full-length patatin-like phospholipase domain containing 2 (cDNA clone MGC:29206 IMAGE:5027544), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets. Exhibits a strong preference for the hydrolysis of long-chain fatty acid esters at the sn-2 position of the glycerol backbone. Also has acylglycerol transacylase activity. Acts coordinately with LIPE/HLS and DGAT2 within the lipolytic cascade. Regulates adiposome size and may be involved in the degradation of adiposomes. May play an important role in energy homeostasis. May play a role in the response of the organism to starvation, enhancing hydrolysis of triglycerides and providing free fatty acids to other tissues to be oxidized in situations of energy depletion.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 75.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Pnpla2 patatin-like phospholipase domain containing 2 [ Mus musculus (house mouse) ]
• Official Symbol: Pnpla2
• Synonyms: Pnpla2; patatin-like phospholipase domain containing 2; At; Atgl; desn; TTS-2.2; 0610039C21Rik; 1110001C14Rik; patatin-like phospholipase domain-containing protein 2; adipose triglyceride lipase; desnutrin; transport-secretion protein; triglyceride hydrolase; EC 3.1.1.3
• Gene ID: 66853
• mRNA Refseq: NM_025802
• Protein Refseq: NP_080078
• UniProt ID: Q8BJ56