Recombinant Mouse Poli Protein, Myc/DDK-tagged
Cat.No. : | Poli-4990M |
Product Overview : | Purified recombinant protein of mouse full-length polymerase (DNA directed), iota (Poli), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Error-prone DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Favors Hoogsteen base-pairing in the active site. Inserts the correct base with high-fidelity opposite an adenosine template. Exhibits low fidelity and efficiency opposite a thymidine template, where it will preferentially insert guanosine. May play a role in hypermutation of immunogobulin genes. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but may not have lyase activity. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 75.1 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Poli polymerase (DNA directed), iota [ Mus musculus (house mouse) ] |
Official Symbol : | Poli |
Synonyms : | POLI; polymerase (DNA directed), iota; DNA polymerase iota; RAD30 homolog B; Rad30b |
Gene ID : | 26447 |
mRNA Refseq : | NM_001136090 |
Protein Refseq : | NP_001129562 |
UniProt ID : | Q6R3M4 |
Products Types
◆ Recombinant Protein | ||
POLI-6911M | Recombinant Mouse POLI Protein, His (Fc)-Avi-tagged | +Inquiry |
POLI-1526H | Recombinant Human POLI protein | +Inquiry |
POLI-1834H | Recombinant Human POLI, His-tagged | +Inquiry |
POLI-1835H | Recombinant Human POLI protein, GST-tagged | +Inquiry |
POLI-2561Z | Recombinant Zebrafish POLI | +Inquiry |
◆ Lysates | ||
POLI-3046HCL | Recombinant Human POLI 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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