Recombinant Mouse Prmt8 Protein, Myc/DDK-tagged

• Cat.No.: Prmt8-5136M
• Product Overview: Purified recombinant protein of mouse full-length protein arginine N-methyltransferase 8 (Prmt8), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: S-adenosyl-L-methionine-dependent and membrane-associated arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA) in proteins such as NIFK, myelin basic protein, histone H4, H2A and H2A/H2B dimer. Able to mono- and dimethylate EWS protein; however its precise role toward EWS remains unclear as it still interacts with fully methylated EWS.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 45.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Prmt8 protein arginine N-methyltransferase 8 [ Mus musculus (house mouse) ]
• Official Symbol: Prmt8
• Synonyms: PRMT8; protein arginine N-methyltransferase 8; HMT1 hnRNP methyltransferase-like 3; protein arginine N-methyltransferase 4; heterogeneous nuclear ribonucleoprotein methyltransferase-like 4; heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4; Hrmt1l3; Hrmt1l4
• Gene ID: 381813
• mRNA Refseq: NM_201371
• Protein Refseq: NP_958759
• UniProt ID: Q6PAK3