Recombinant Mouse Psmd10 Protein, Myc/DDK-tagged
Cat.No. : | Psmd10-5189M |
Product Overview : | Purified recombinant protein of mouse full-length proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 (Psmd10), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Acts as a chaperone during the assembly of the 26S proteasome, specifically of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD10:PSMC4:PSMC5:PAAF1 module which probably assembles with a PSMD5:PSMC2:PSMC1:PSMD2 module. Independently of the proteasome, regulates EGF-induced AKT activation through inhibition of the RHOA/ROCK/PTEN pathway, leading to prolonged AKT activation. Plays an important role in RAS-induced tumorigenesis. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 25.1 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Psmd10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 [ Mus musculus (house mouse) ] |
Official Symbol : | Psmd10 |
Synonyms : | PSMD10; proteasome (prosome, macropain) 26S subunit, non-ATPase, 10; 26S proteasome non-ATPase regulatory subunit 10; gankyrin; proteasome subunit p28; proteosome subunit p28; 26S proteasome regulatory subunit p28; proteosome (prosome, macropain) 26S subunit, non-ATPase, 10; AW554874 |
Gene ID : | 53380 |
mRNA Refseq : | NM_016883 |
Protein Refseq : | NP_058579 |
UniProt ID : | Q9Z2X2 |
Products Types
◆ Recombinant Protein | ||
PSMD10-4444R | Recombinant Rat PSMD10 Protein, His (Fc)-Avi-tagged | +Inquiry |
PSMD10-3486R | Recombinant Rhesus Macaque PSMD10 Protein, His (Fc)-Avi-tagged | +Inquiry |
PSMD10-5240C | Recombinant Chicken PSMD10 | +Inquiry |
PSMD10-6927H | Recombinant Human Proteasome (prosome, macropain) 26S Subunit, Non-ATPase, 10 | +Inquiry |
PSMD10-6050H | Recombinant Human PSMD10 Protein (Met1-Gly226), N-GST tagged | +Inquiry |
◆ Lysates | ||
PSMD10-2756HCL | Recombinant Human PSMD10 293 Cell Lysate | +Inquiry |
PSMD10-2755HCL | Recombinant Human PSMD10 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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