Recombinant Mouse Psmd2 Protein, Myc/DDK-tagged
Cat.No. : | Psmd2-5193M |
Product Overview : | Purified recombinant protein of mouse full-length proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 (Psmd2), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
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Description : | Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 100.2 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Psmd2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 [ Mus musculus (house mouse) ] |
Official Symbol : | Psmd2 |
Synonyms : | PSMD2; proteasome (prosome, macropain) 26S subunit, non-ATPase, 2; 26S proteasome non-ATPase regulatory subunit 2; testis expressed gene 190; 26S proteasome subunit p97; 26S proteasome regulatory subunit S2; 26S proteasome regulatory subunit RPN1; Tex190; TEG-190; AA407121; 9430095H01Rik |
Gene ID : | 21762 |
mRNA Refseq : | NM_134101 |
Protein Refseq : | NP_598862 |
UniProt ID : | Q8VDM4 |
Products Types
◆ Recombinant Protein | ||
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PSMD2-2147C | Recombinant Chicken PSMD2 | +Inquiry |
PSMD2-6044H | Recombinant Human PSMD2 Protein (Asp645-Val872), His tagged | +Inquiry |
PSMD2-10829Z | Recombinant Zebrafish PSMD2 | +Inquiry |
◆ Lysates | ||
PSMD2-2750HCL | Recombinant Human PSMD2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionPSMD2 helps maintain cellular homeostasis by regulating the turnover of proteins, controlling their abundance and activity.
Targeting components of the ubiquitin-proteasome system, including PSMD2, is explored for potential therapeutic interventions in certain diseases.
PSMD2 is a subunit of the 26S proteasome, a cellular complex involved in protein degradation.
Dysregulation of proteasomal function, including PSMD2, is implicated in various diseases, such as neurodegenerative disorders and cancer.
Yes, PSMD2, as part of the 26S proteasome, contributes to protein quality control by degrading misfolded or damaged proteins.
PSMD2 plays a crucial role in the ubiquitin-proteasome system, participating in targeted protein degradation.
PSMD2 is typically found in the nucleus and cytoplasm, reflecting its involvement in cellular protein degradation processes.
Customer Reviews (3)
Write a reviewThe product's stability over extended periods was a significant advantage for our long-term research projects.
Consistency in its performance over time made it a reliable resource for ongoing experiments.
The absence of adverse effects on cells or organisms underscored the product's safety and suitability for biological research.
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