Recombinant Mouse Pstpip1 Protein, Myc/DDK-tagged
Cat.No. : | Pstpip1-5210M |
Product Overview : | Purified recombinant protein of mouse full-length proline-serine-threonine phosphatase-interacting protein 1 (Pstpip1), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Involved in regulation of the actin cytoskeleton. May regulate WAS actin-bundling activity. Bridges the interaction between ABL1 and PTPN18 leading to ABL1 dephosphorylation. May play a role as a scaffold protein between PTPN12 and WAS and allow PTPN12 to dephosphorylate WAS. Has the potential to physically couple CD2 and CD2AP to WAS. Acts downstream of CD2 and CD2AP to recruit WAS to the T-cell:APC contact site so as to promote the actin polymerization required for synapse induction during T-cell activation. Down-regulates CD2-stimulated adhesion through the coupling of PTPN12 to CD2. Also has a role in innate immunity and the inflammatory response. Recruited to inflammasomes by MEFV. Induces formation of pyroptosomes, large supramolecular structures composed of oligomerized PYCARD dimers which form prior to inflammatory apoptosis. Binding to MEFV allows MEFV to bind to PYCARD and facilitates pyroptosome formation. Regulates endocytosis and cell migration in neutrophils. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 47.6 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Pstpip1 proline-serine-threonine phosphatase-interacting protein 1 [ Mus musculus (house mouse) ] |
Official Symbol : | Pstpip1 |
Synonyms : | PSTPIP1; proline-serine-threonine phosphatase-interacting protein 1; PEST phosphatase-interacting protein 1; def-2; CD2BP1 |
Gene ID : | 19200 |
mRNA Refseq : | NM_011193 |
Protein Refseq : | NP_035323 |
UniProt ID : | P97814 |
Products Types
◆ Recombinant Protein | ||
PSTPIP1-7237M | Recombinant Mouse PSTPIP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
PSTPIP1-204H | Recombinant Human proline-serine-threonine phosphatase interacting protein 1, His-tagged | +Inquiry |
PSTPIP1-13616M | Recombinant Mouse PSTPIP1 Protein | +Inquiry |
◆ Lysates | ||
PSTPIP1-2732HCL | Recombinant Human PSTPIP1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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