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Recombinant Mouse Ptpn2 protein, His & T7-tagged

Cat.No. : Ptpn2-8089M
Product Overview : Recombinant Mouse Ptpn2 aa. (Met1~Glu237 (Accession # Q06180)) fused with N-terminal His & T7 tag was produced in E. coli cells.
  • Specification
  • Gene Information
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Source : E. coli
Species : Mouse
Tag : His & T7
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 31.3kDa.
Protein length : Met1~Glu237 (Accession # Q06180)
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >95%
Characteristic : The isoelectric point is 5.7.
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage Buffer : Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
Reconstitution : Reconstitute in sterile ddH2O.
Gene Name : Ptpn2 protein tyrosine phosphatase, non-receptor type 2 [ Mus musculus (house mouse) ]
Official Symbol : Ptpn2
Synonyms : Ptpn2; protein tyrosine phosphatase, non-receptor type 2; Ptpt; TC-PTP; AI325124; tyrosine-protein phosphatase non-receptor type 2; MPTP; T cell protein-tyrosine phosphatase; protein-tyrosine phosphatase PTP-2
Gene ID : 19255
mRNA Refseq : NM_001127177.1
Protein Refseq : NP_001120649.1
UniProt ID : Q06180

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What is the therapeutic effect of specific PTPN2 inhibitors on inflammatory diseases? 09/30/2022

PTPN2 inhibitors can inhibit certain signaling pathways in the inflammatory response, thereby playing a role in the treatment of inflammatory diseases.

Is there a soluble PTPN2 protein? 01/06/2022

Yes, soluble PTPN2 proteins exist that can be detected in extracellular fluids and may play a role in regulating cell-to-cell communication and signal transduction.

What is the modulating effect of soluble PTPN2 protein on immune response? 03/17/2021

PTPN2 protein can interact with receptors on the surface of immune cells to regulate the activation and function of immune cells, thereby playing a role in regulating immune responses.

What is the role of PTPN2 protein in autoimmune diseases? 01/15/2021

Studies have shown that PTPN2 protein plays a certain role in autoimmune diseases, and its expression level may be related to the occurrence and progression of the disease.

Are specific PTPN2 inhibitors useful for the treatment of autoimmune diseases? 11/02/2020

Specific PTPN2 inhibitors can inhibit certain abnormal signaling pathways in autoimmune diseases, thereby playing a role in the treatment of autoimmune diseases.

How does PTPN2 protein regulate immune response? 04/16/2020

This protein can interact with a variety of immune molecules, such as T cell receptors (TCRs) and B cell receptors (BCRs), to regulate immune responses by regulating their phosphorylation status.

Customer Reviews (3)

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Reviews
10/06/2022

    Repeatability is good, and the results of multiple experiments are consistent.

    08/10/2022

      The impurities are very well removed and the purity is very high.

      04/14/2021

        Performance is very stable and the price is very reasonable. I would definitely buy this product again.

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