Recombinant Mouse Rasgrp1 Protein, Myc/DDK-tagged
Cat.No. : | Rasgrp1-5389M |
Product Overview : | Purified recombinant protein of mouse full-length RAS guanyl releasing protein 1 (Rasgrp1), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Functions as a calcium- and diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. Activates the Erk/MAP kinase cascade. Regulates T-cell/B-cell development, homeostasis and differentiation by coupling T-lymphocyte/B-lymphocyte antigen receptors to Ras. Regulates NK cell cytotoxicity and ITAM-dependent cytokine production by activation of Ras-mediated ERK and JNK pathways. Functions in mast cell degranulation and cytokine secretion, regulating FcERI-evoked allergic responses. May also function in differentiation of other cell types. Proto-oncogene, which promotes T-cell lymphomagenesis when its expression is deregulated. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 90.8 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Rasgrp1 RAS guanyl releasing protein 1 [ Mus musculus (house mouse) ] |
Official Symbol : | Rasgrp1 |
Synonyms : | RASGRP1; RAS guanyl releasing protein 1; RAS guanyl-releasing protein 1; calDAG-GEFII; calcium and DAG-regulated guanine nucleotide exchange factor II; Rasgrp |
Gene ID : | 19419 |
mRNA Refseq : | NM_011246 |
Protein Refseq : | NP_035376 |
UniProt ID : | Q9Z1S3 |
Products Types
◆ Recombinant Protein | ||
RASGRP1-4596R | Recombinant Rat RASGRP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
RASGRP1-1860H | Recombinant Human RASGRP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
RASGRP1-7437M | Recombinant Mouse RASGRP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
RASGRP1-2922H | Recombinant Human RASGRP1 protein, His-tagged | +Inquiry |
RASGRP1-4937R | Recombinant Rat RASGRP1 Protein | +Inquiry |
◆ Lysates | ||
RASGRP1-2506HCL | Recombinant Human RASGRP1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket