Recombinant Mouse Rcc1 Protein, MYC/DDK-tagged Rcc1-019M

Recombinant Mouse Rcc1 Protein, MYC/DDK-tagged

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Recombinant Mouse Rcc1 Protein, MYC/DDK-tagged

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Cat.No. : Rcc1-019M
Product Overview : Purified recombinant protein of full-length mouse regulator of chromosome condensation 1 (Rcc1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
Description : Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP, and thereby plays an important role in RAN-mediated functions in nuclear import and mitosis. Contributes to the generation of high levels of chromosome-associated, GTP-bound RAN, which is important for mitotic spindle assembly and normal progress through mitosis. Via its role in maintaining high levels of GTP-bound RAN in the nucleus, contributes to the release of cargo proteins from importins after nuclear import. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA.
Source : HEK293T
Species : Mouse
Tag : MYC/DDK
Molecular Mass : 44.9 kDa
Purity : >80%, as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 ug/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Rcc1 regulator of chromosome condensation 1 [ Mus musculus (house mouse) ]
Official Symbol : Rcc1
Synonyms : Rcc1; regulator of chromosome condensation 1; Chc1; AI326872; 4931417M11Rik; regulator of chromosome condensation; chromosome condensation protein 1
Gene ID : 100088
mRNA Refseq : NM_133878
Protein Refseq : NP_598639
UniProt ID : Q8VE37

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