Recombinant Mouse Retnlb, FLAG-tagged

• Cat.No.: Retnlb-450M
• Product Overview: Mouse RELM-β (aa 24-105) is fused at the N-terminus to a FLAG-tag.

Specification

• Species: Mouse
• Source: HEK293
• Tag: Flag
• Protein Length: 24-105 a.a.
• Description: Resistin-like molecule beta (RELM-beta; Found in inflammatory zone 2; FIZZ2) is a homodimeric protein belonging to the RELM/FIZZ family of cysteine rich secretory proteins. The gut-derived hormone RELM-beta is a regulator of insulin sensitivity, possibly involved in insulin resistance induced by obesity. RELM-beta was shown to impair insulin signaling via the activations of classic MAPKs, and increased expression of RELM-beta was involved in the pathogenesis of glucose intolerance and hyperlipidemia in insulin-resistant models.
• Form: Liquid. 0.2μm-filtered solution in PBS, pH 7.2.
• Molecular Mass: ~12kDa (SDS-PAGE)
• Purity: ≥90% (SDS-PAGE)
• Stability: Working aliquots are stable for up to 3 months when stored at -20°C.
• Storage: Short Term Storage: +4°C; Long Term Storage: -20°C. After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
• Concentration: 1mg/ml

Gene Information

• Gene Name: Retnlb resistin like beta [ Mus musculus ]
• Official Symbol: Retnlb
• Synonyms: RETNLB; resistin like beta; resistin-like beta; resistin-like molecule beta; found in inflammatory zone 2; cysteine-rich secreted protein FIZZ2; cysteine-rich secreted protein A12-beta; Xcp3; Fizz2; Relmb; RELMbeta; 9030012B21Rik
• Gene ID: 57263
• mRNA Refseq: NM_023881
• Protein Refseq: NP_076370
• Function: hormone activity