Recombinant Mouse Rheb Protein, Myc/DDK-tagged
Cat.No. : | Rheb-5504M |
Product Overview : | Purified recombinant protein of mouse full-length Ras homolog enriched in brain (Rheb), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
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Description : | Activates the protein kinase activity of mTORC1, and thereby plays a role in the regulation of apoptosis. Stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling. Has low intrinsic GTPase activity. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 20.5 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Rheb Ras homolog enriched in brain [ Mus musculus (house mouse) ] |
Official Symbol : | Rheb |
Synonyms : | RHEB; Ras homolog enriched in brain; GTP-binding protein Rheb; RAS-homolog enriched in brain |
Gene ID : | 19744 |
mRNA Refseq : | NM_053075 |
Protein Refseq : | NP_444305 |
UniProt ID : | Q921J2 |
Products Types
◆ Recombinant Protein | ||
RHEB-4691R | Recombinant Rat RHEB Protein, His (Fc)-Avi-tagged | +Inquiry |
RHEB-1181H | Recombinant Human RHEB Protein, MYC/DDK-tagged | +Inquiry |
RHEB-3701R | Recombinant Rhesus Macaque RHEB Protein, His (Fc)-Avi-tagged | +Inquiry |
RHEB-3884R | Recombinant Rhesus monkey RHEB Protein, His-tagged | +Inquiry |
RHEB-31325TH | Recombinant Human RHEB, T7 -tagged | +Inquiry |
◆ Lysates | ||
RHEB-001HCL | Recombinant Human RHEB cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionRHEB directly interacts with the mTOR pathway, a key regulator of cell growth. Understanding this interaction provides insights for developing drugs that target this pathway in diseases like cancer.
Some experimental drugs targeting RHEB are in preclinical development, showing promise in modulating cell growth and survival.
RHEB's involvement in cell growth makes it a potential target for cancer therapy. Understanding its role may lead to the development of targeted therapies.
Research is underway to evaluate the therapeutic potential of targeting RHEB in cancer treatment, with several clinical trials exploring its role as a therapeutic target.
Dysregulation of RHEB is associated with various diseases, including cancer and neurological disorders, due to its impact on cell growth and survival pathways.
Customer Reviews (3)
Write a reviewResearchers using RHEB protein can benefit from its high purity and quality, ensuring reliable results.
the RHEB protein is available in different formats, including recombinant and purified variants.
This flexibility allows researchers to select the most suitable form for their particular experimental setup, enhancing the efficiency and accuracy of their trials.
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