Recombinant Mouse Ripor2 Protein, Myc/DDK-tagged

• Cat.No.: Ripor2-5523M
• Product Overview: Purified recombinant protein of mouse full-length RHO family interacting cell polarization regulator 2 (Ripor2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Acts as an inhibitor of the small GTPase RHOA and plays several roles in the regulation of myoblast and hair cell differentiation, lymphocyte T proliferation and neutrophil polarization. Plays a role in fetal mononuclear myoblast differentiation by promoting filopodia and myotube formation. Maintains naive T lymphocytes in a quiescent state and prevents chemokine-induced T lymphocyte responses, such as cell adhesion, polarization and migration. Involved also in the regulation of neutrophil polarization, chemotaxis and adhesion. Required for normal development of inner and outer hair cell stereocilia within the cochlea of the inner ear. Plays a role for maintaining the structural organization of the basal domain of stereocilia. Involved in mechanosensory hair cell function. Required for normal hearing.
• Molecular Mass: 119 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ripor2 RHO family interacting cell polarization regulator 2 [ Mus musculus (house mouse) ]
• Official Symbol: Ripor2
• Synonyms: Ripor2; RHO family interacting cell polarization regulator 2; Fam65; Fam65b; rho family-interacting cell polarization regulator 2; family with sequence similarity 65, member B; protein FAM65B
• Gene ID: 193385
• mRNA Refseq: NM_029679
• Protein Refseq: NP_083955
• UniProt ID: Q80U16