Recombinant Mouse Rp1 Protein, His-tagged

• Cat.No.: Rp1-2028M
• Product Overview: Recombinant Mouse Rp1 Protein (Lys35-Asp236) with N-His tag was expressed in E. coli.

Specification

• Description: This gene encodes a member of the doublecortin family. The protein encoded by this gene contains two doublecortin domains, which bind microtubules and regulate microtubule polymerization. The encoded protein is a photoreceptor microtubule-associated protein and is required for correct stacking of outer segment disc. This protein and the RP1L1 protein, another retinal-specific protein, play essential and synergistic roles in affecting photosensitivity and outer segment morphogenesis of rod photoreceptors. Because of its response to in vivo retinal oxygen levels, this protein was initially named ORP1 (oxygen-regulated protein-1). This protein was subsequently designated RP1 (retinitis pigmentosa 1) when it was found that mutations in this gene cause autosomal dominant retinitis pigmentosa. Mutations in this gene also cause autosomal recessive retinitis pigmentosa.
• Source: E. coli
• Species: Mouse
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 26.3 kDa
  Accurate Molecular Mass: 31 kDa
• Protein length: Lys35-Asp236
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: Rp1 retinitis pigmentosa 1 (human) [ Mus musculus (house mouse) ]
• Official Symbol: Rp1
• Synonyms: Rp1; retinitis pigmentosa 1 (human); Orp1; Rp1h; Dcdc3; mG145; Gm38717; oxygen-regulated protein 1; lipoxygenase homology domain-containing protein 1; retinitis pigmentosa 1 homolog; retinitis pigmentosa RP1 protein homolog
• Gene ID: 19888
• mRNA Refseq: NM_011283
• Protein Refseq: NP_035413
• UniProt ID: P56716