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Recombinant Mouse S100a11 Protein, Myc/DDK-tagged

Cat.No. : S100a11-5665M
Product Overview : Purified recombinant protein of mouse full-length S100 calcium binding protein A11 (S100a11), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
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Description : Facilitates the differentiation and the cornification of keratinocytes.
Source : HEK293T
Species : Mouse
Tag : Myc&DDK
Molecular Mass : 11.5 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : S100a11 S100 calcium binding protein A11 [ Mus musculus (house mouse) ]
Official Symbol : S100a11
Synonyms : S100A11; S100 calcium binding protein A11 (calgizzarin); protein S100-A11; EMAP; calizzarin; calgizzarin; protein S100-C; S100 calcium binding protein A14; S100 calcium-binding protein A11; endothelial monocyte-activating polypeptide; S100 calcium binding protein A11 (calizzarin); endothelial monocyte activating polypeptide 1; cal; EMAPI; Emap1; S100c; S100a14; MGC107585
Gene ID : 20195
mRNA Refseq : NM_016740
Protein Refseq : NP_058020
UniProt ID : P50543

Not For Human Consumption!

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Customer Reviews (3)

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Reviews
03/09/2021

    Quality product, delivered on time—perfect!

    01/30/2019

      Fantastic quality, hassle-free delivery!

      10/16/2018

        A+ for both product quality and excellent service!

        Q&As (5)

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        Can you elaborate on the role of S100A11 in cellular signaling pathways, particularly those involved in cancer progression and metastasis? 01/12/2021

        S100A11 participates in multiple signaling pathways, influencing cancer progression and metastasis. It interacts with proteins involved in cell motility, invasion, and angiogenesis, contributing to the malignant phenotype.

        How does S100A11 contribute to cellular differentiation, and are there specific target genes or pathways involved in this process? 05/23/2020

        S100A11 plays a role in cellular differentiation, influencing specific target genes and pathways. Its involvement in differentiation programs is context-dependent and varies across cell types.

        How is S100A11 expression regulated, and what are the transcriptional and post-translational mechanisms influencing its activity? 04/07/2019

        S100A11 expression is regulated at transcriptional and post-translational levels. Transcription factors and signaling pathways control its mRNA levels, while post-translational modifications such as phosphorylation modulate its activity.

        In neurodegenerative diseases, is there evidence of S100A11 involvement, and what are the potential mechanisms linking this protein to neurological pathology? 11/14/2018

        Emerging evidence suggests a potential role for S100A11 in neurodegenerative diseases. The mechanisms linking S100A11 to neurological pathology involve its interactions with proteins and signaling cascades.

        What is S100A11, and what is its cellular localization and physiological role? 08/29/2018

        S100A11 is a member of the S100 protein family, predominantly located in the cytoplasm and nucleus. Its physiological roles include regulation of cell proliferation, differentiation, and apoptosis.

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