Recombinant Mouse Scg5 Protein, Myc/DDK-tagged

• Cat.No.: Scg5-5709M
• Product Overview: Purified recombinant protein of mouse full-length secretogranin V (Scg5), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 24.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Scg5 secretogranin V [ Mus musculus (house mouse) ]
• Official Symbol: Scg5
• Synonyms: SCG5; secretogranin V; neuroendocrine protein 7B2; secretogranin-5; secretory granule endocrine protein I; secretory granule neuroendocrine protein 1, 7B2 protein; 7B2; Sgne1; Sgne-1; AI325031
• Gene ID: 20394
• mRNA Refseq: NM_009162
• Protein Refseq: NP_033188
• UniProt ID: P12961