Recombinant Mouse Sf3b3 Protein, MYC/DDK-tagged
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| Cat.No. : | Sf3b3-194M |
| Product Overview : | Purified recombinant protein of full-length mouse splicing factor 3b, subunit 3 (Sf3b3), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
| Description : | Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron. |
| Source : | HEK293T |
| Species : | Mouse |
| Tag : | MYC/DDK |
| Molecular Mass : | 136 kDa |
| Purity : | >80%, as determined by SDS-PAGE and Coomassie blue staining |
| Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Storage : | Store at -80 centigrade after receiving vials. |
| Concentration : | >50 ug/mL as determined by microplate BCA method |
| Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
| Gene Name : | Sf3b3 splicing factor 3b, subunit 3 [ Mus musculus (house mouse) ] |
| Official Symbol : | Sf3b3 |
| Synonyms : | Sf3b3; splicing factor 3b, subunit 3; RSE1; SAP130; SF3b130; AA409318; mKIAA0017; D8Ertd633e; 1810061H24Rik; 5730409A01Rik; splicing factor 3B subunit 3; SAP 130; pre-mRNA-splicing factor SF3b 130 kDa subunit; spliceosome-associated protein 130 |
| Gene ID : | 101943 |
| mRNA Refseq : | NM_133953 |
| Protein Refseq : | NP_598714 |
| UniProt ID : | Q921M3 |
◆ Recombinant Protein
| SF3B3-2509H | Recombinant Human SF3B3 Protein, MYC/DDK-tagged | +Inquiry |
| SF3B3-2613H | Recombinant Human SF3B3, His-tagged | +Inquiry |
| Sf3b3-23M | Recombinant Mouse Sf3b3 Protein, His-tagged | +Inquiry |
| SF3B3-12665Z | Recombinant Zebrafish SF3B3 | +Inquiry |
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◆ Lysates
| SF3B3-1916HCL | Recombinant Human SF3B3 293 Cell Lysate | +Inquiry |
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