Recombinant Mouse Sh2b3 Protein, MYC/DDK-tagged Sh2b3-1332M

Recombinant Mouse Sh2b3 Protein, MYC/DDK-tagged


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Recombinant Mouse Sh2b3 Protein, MYC/DDK-tagged

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Cat.No. : Sh2b3-1332M
Product Overview : Purified recombinant protein of full-length mouse SH2B adaptor protein 3 (Sh2b3), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.
Description : This gene encodes a member of the SH2B family of adapter proteins that play an important role in T cell receptor signaling. This gene is preferentially expressed in hematopoietic stem cells, hematopoietic progenitors, pre and immature B cells, as well as megakaryocytes and mastocytes. In hematopoietic stem cells, the encoded protein is a key regulator of self-renewal, proliferation and apoptosis. Mice lacking the encoded protein exhibit pre and immature B cell expansion in spleen and the bone marrow. Alternative splicing results in multiple transcript variants encoding different isoforms.
Source : HEK293T
Species : Mouse
Molecular Mass : 60.9 kDa
Purity : >80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 µg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Sh2b3 SH2B adaptor protein 3 [ Mus musculus (house mouse) ]
Official Symbol : Sh2b3
Synonyms : Sh2b3; SH2B adaptor protein 3; Lnk; AI429800; SH2B adapter protein 3; linker of T-cell receptor pathways; lymphocyte-specific adapter protein Lnk; signal transduction protein Lnk
Gene ID : 16923
mRNA Refseq : NM_008507
Protein Refseq : NP_032533
UniProt ID : O09039

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