Recombinant Mouse Sik2 Protein, Myc/DDK-tagged

• Cat.No.: Sik2-5878M
• Product Overview: Purified recombinant protein of mouse full-length salt inducible kinase 2 (Sik2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Phosphorylates 'Ser-789' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and inhibiting activity of TORCs, the CREB-specific coactivators, like CRTC2/TORC2 and CRTC3/TORC3 in response to cAMP signaling.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 104.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Sik2 salt inducible kinase 2 [ Mus musculus (house mouse) ]
• Official Symbol: Sik2
• Synonyms: SIK2; salt inducible kinase 2; serine/threonine-protein kinase SIK2; SIK-2; SNF1-like kinase 2; salt-inducible kinase 2; salt induceable kinase 2; salt-inducible protein kinase 2; serine/threonine-protein kinase SNF1-like kinase 2; Snf1lk2; G630080D20Rik
• Gene ID: 235344
• mRNA Refseq: NM_178710
• Protein Refseq: NP_848825
• UniProt ID: Q8CFH6