Recombinant Mouse Skap1 Protein, Myc/DDK-tagged

• Cat.No.: Skap1-5893M
• Product Overview: Purified recombinant protein of mouse full-length src family associated phosphoprotein 1 (Skap1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Positively regulates T-cell receptor signaling by enhancing the MAP kinase pathway. Required for optimal conjugation between T-cells and antigen-presenting cells by promoting the clustering of integrin ITGAL on the surface of T-cells. May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 41 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Skap1 src family associated phosphoprotein 1 [ Mus musculus (house mouse) ]
• Official Symbol: Skap1
• Synonyms: SKAP1; src family associated phosphoprotein 1; src kinase-associated phosphoprotein 1; src family-associated phosphoprotein 1; ortholog of human src family associated phosphoprotein 1 SCAP1; Scap1; Skap-55; 1700091G21Rik
• Gene ID: 78473
• mRNA Refseq: NM_001033186
• Protein Refseq: NP_001028358
• UniProt ID: Q3UUV5