"Sptlc2" Related Products

Recombinant Mouse Sptlc2 Protein, His-tagged

Cat.No.: Sptlc2-679M
Product Overview: Recombinant Mouse Sptlc2(Glu453~Asp560) fused with His tag at N-terminal was expressed in E. coli.
Description: This gene encodes a long chain base subunit of serine palmitoyltransferase. The enzyme, serine palmitoyltransferase, consists of two different subunits, and is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. A mutant allele of this gene in mice is used as a model for the human disease 'Susceptibilty to Psoriasis 1'. Mutations in the human gene are associated with hereditary sensory neuropathy type I.
Source: E. coli
Species: Mouse
Tag : His
Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Molecular Mass: 15.9kDa
Protein length: Glu453~Asp560
Endotoxin: <1.0EU per 1µg (determined by the LAL method)
Purity: > 94%
Applications: Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution: Reconstitute in PBS or others.
Gene Name: Sptlc2 serine palmitoyltransferase, long chain base subunit 2 [ Mus musculus ]
Official Symbol: Sptlc2
Synonyms: SPTLC2; serine palmitoyltransferase, long chain base subunit 2; serine palmitoyltransferase 2; LCB 2; LCB2a; SPT 2; serine-palmitoyl-CoA transferase 2; long chain base biosynthesis protein 2; long chain base biosynthesis protein 2a; LCB2; AI173915; mKIAA0526;
Gene ID: 20773
mRNA Refseq: NM_011479
Protein Refseq: NP_035609
UniProt ID: P97363

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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