Recombinant Mouse Srsf1 Protein, MYC/DDK-tagged
Cat.No. : | Srsf1-483M |
Product Overview : | Purified recombinant protein of full-length mouse serine/arginine-rich splicing factor 1 (Srsf1), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
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Description : | The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding different isoforms have been found for this gene. |
Source : | HEK293T |
Species : | Mouse |
Tag : | MYC/DDK |
Molecular Mass : | 28.2 kDa |
Purity : | >80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Srsf1 serine and arginine-rich splicing factor 1 [ Mus musculus (house mouse) ] |
Official Symbol : | Srsf1 |
Synonyms : | Srsf1; serine and arginine-rich splicing factor 1; Asf; Sf2; Sfrs1; AI482334; AW491331; 1110054N12Rik; 5730507C05Rik; 6330415C05Rik; serine/arginine-rich splicing factor 1; ASF/SF2; pre-mRNA-splicing factor SRp30a; splicing factor, arginine/serine-rich 1 (ASF/SF2) |
Gene ID : | 110809 |
mRNA Refseq : | NM_173374 |
Protein Refseq : | NP_775550 |
UniProt ID : | Q6PDM2 |
Products Types
◆ Recombinant Protein | ||
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SRSF1-4289R | Recombinant Rhesus Macaque SRSF1 Protein, His (Fc)-Avi-tagged | +Inquiry |
SRSF1-809H | Recombinant Human SRSF1 Protein (2-248 aa), His-SUMO-tagged | +Inquiry |
SRSF1-8734M | Recombinant Mouse SRSF1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
SRSF1-1910HCL | Recombinant Human SFRS1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionWhile there are no approved therapies specifically targeting SRSF1, preclinical studies are investigating its potential as a therapeutic target.
Studies suggest that SRSF1 expression levels could potentially serve as a biomarker for cancer diagnosis and prognosis.
Yes, SRSF1 has also been implicated in neurodegenerative diseases, such as spinal muscular atrophy.
SRSF1 regulates alternative splicing by binding to specific RNA sequences and influencing splice site selection.
SRSF1 interacts with other splicing factors and signaling proteins to regulate gene expression and cellular functions.
Customer Reviews (3)
Write a reviewTheir commitment to providing technical support is unparalleled, and their expertise can prove invaluable in navigating any challenges or troubleshooting that may arise during my experiments.
This commitment to staying at the forefront of research translates directly to the quality and performance of the SRSF1 protein in my trials.
They monitor the latest advancements in the field and incorporate new findings into the production and characterization of the protein.
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