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Recombinant Mouse Srsf1 Protein, MYC/DDK-tagged

Cat.No. : Srsf1-483M
Product Overview : Purified recombinant protein of full-length mouse serine/arginine-rich splicing factor 1 (Srsf1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
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  • Gene Information
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Description : The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding different isoforms have been found for this gene.
Source : HEK293T
Species : Mouse
Tag : MYC/DDK
Molecular Mass : 28.2 kDa
Purity : >80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Srsf1 serine and arginine-rich splicing factor 1 [ Mus musculus (house mouse) ]
Official Symbol : Srsf1
Synonyms : Srsf1; serine and arginine-rich splicing factor 1; Asf; Sf2; Sfrs1; AI482334; AW491331; 1110054N12Rik; 5730507C05Rik; 6330415C05Rik; serine/arginine-rich splicing factor 1; ASF/SF2; pre-mRNA-splicing factor SRp30a; splicing factor, arginine/serine-rich 1 (ASF/SF2)
Gene ID : 110809
mRNA Refseq : NM_173374
Protein Refseq : NP_775550
UniProt ID : Q6PDM2

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Are there any clinical trials targeting SRSF1? 03/20/2022

While there are no approved therapies specifically targeting SRSF1, preclinical studies are investigating its potential as a therapeutic target.

Can SRSF1 be used as a biomarker for cancer? 01/12/2022

Studies suggest that SRSF1 expression levels could potentially serve as a biomarker for cancer diagnosis and prognosis.

Is SRSF1 involved in other diseases besides cancer? 08/01/2020

Yes, SRSF1 has also been implicated in neurodegenerative diseases, such as spinal muscular atrophy.

How does SRSF1 impact pre-mRNA splicing? 03/21/2019

SRSF1 regulates alternative splicing by binding to specific RNA sequences and influencing splice site selection.

How does SRSF1 interact with other proteins in the cell? 01/17/2016

SRSF1 interacts with other splicing factors and signaling proteins to regulate gene expression and cellular functions.

Customer Reviews (3)

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Reviews
03/21/2023

    Their commitment to providing technical support is unparalleled, and their expertise can prove invaluable in navigating any challenges or troubleshooting that may arise during my experiments.

    07/17/2021

      This commitment to staying at the forefront of research translates directly to the quality and performance of the SRSF1 protein in my trials.

      03/17/2021

        They monitor the latest advancements in the field and incorporate new findings into the production and characterization of the protein.

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