Recombinant Mouse Stk11 Protein, His-tagged

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Recombinant Mouse Stk11 Protein, His-tagged

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Cat.No. : Stk11-668M
Product Overview : Recombinant Mouse Stk11(Tyr49~Phe309) fused with His tag at N-terminal was expressed in E. coli.
Description : This gene encodes a member of the serine/threonine kinase family. The encoded protein, a known tumor suppressor, activates (via phosphorylation) adenine monophosphate-activated protein kinase (AMPK) and AMPK-related kinase proteins. This upstream regulation of the AMPK pathway is thought to regulate a number of different processes, including cell metabolism, cell polarity, apoptosis and DNA damage response. Mutations in a similar gene in human have been associated with Peutz-Jeghers syndrome. Alternative splicing results in multiple transcript variants, including the S isoform which plays a potential role in spermiogenesis.
Source : E. coli
Species : Mouse
Tag : His
Form : PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Molecular Mass : 33.4kDa
Protein length : Tyr49~Phe309
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : >95%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution : Reconstitute in PBS or others.
Figure :

Gene Name : Stk11 serine/threonine kinase 11 [ Mus musculus ]
Official Symbol : Stk11
Synonyms : STK11; serine/threonine kinase 11; serine/threonine-protein kinase STK11; LKB1 short isoform; liver kinase B1 homolog; serine/threonine-protein kinase 11; serine/threonine-protein kinase LKB1; Lkb1; Par-4; mLKB1; R75140; AA408040;
Gene ID : 20869
mRNA Refseq : NM_011492
Protein Refseq : NP_035622
UniProt ID : Q9WTK7
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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