Recombinant Mouse Tiprl Protein, Myc/DDK-tagged
Cat.No. : | Tiprl-6439M |
Product Overview : | Purified recombinant protein of mouse full-length TIP41, TOR signalling pathway regulator-like (S. cerevisiae) (Tiprl), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | May be a allosteric regulator of serine/threonine-protein phosphatase 2A (PP2A). Inhibits catalytic activity of the PP2A(D) core complex in vitro. The PP2A(C):TIPRL complex does not show phosphatase activity. Acts as negative regulator of serine/threonine-protein phosphatase 4 probably by inhibiting the formation of the active PPP4C:PPP4R2 complex; the function is proposed to implicate it in DNA damage response by promoting H2AX phosphorylated on Ser-140 (gamma-H2AX). May play a role in the regulation of ATM/ATR signaling pathway controlling DNA replication and repair. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 31.7 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Tiprl TIP41, TOR signalling pathway regulator-like (S. cerevisiae) [ Mus musculus (house mouse) ] |
Official Symbol : | Tiprl |
Synonyms : | TIPRL; TIP41, TOR signalling pathway regulator-like (S. cerevisiae); TIP41-like protein; 1810011K17Rik |
Gene ID : | 226591 |
mRNA Refseq : | NM_145513 |
Protein Refseq : | NP_663488 |
UniProt ID : | Q8BH58 |
Products Types
◆ Recombinant Protein | ||
TIPRL-2196H | Recombinant Human TIPRL Protein, His (Fc)-Avi-tagged | +Inquiry |
TIPRL-3244H | Recombinant Human TIPRL, GST-tagged | +Inquiry |
TIPRL-10932Z | Recombinant Zebrafish TIPRL | +Inquiry |
◆ Lysates | ||
TIPRL-1057HCL | Recombinant Human TIPRL 293 Cell Lysate | +Inquiry |
TIPRL-1058HCL | Recombinant Human TIPRL 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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