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Recombinant Mouse Tnfrsf1b protein

Cat.No. : Tnfrsf1b-847M
Product Overview : Recombinant Mouse Tnfrsf1b protein was expressed in E.coli.
  • Specification
  • Gene Information
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Description : Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2 (By similarity).
Source : E.coli
Species : Mouse
Form : Lyophilized from a 0.2 µm filtered solution in PBS, pH 7.4.
Bio-activity : Fully biologically active when compared to standard. The ED50 as determined by its ability to inhibit the TNF-α mediated cytotoxicity in the L-929 cells is less than 2 μg/ml, corresponding to a specific activity of > 500 IU/mg in the presence of 0.1 ng/mL of rMuTNF-α.
Molecular Mass : Approximately 25.3 kDa, a single non-glycosylated polypeptide chain containing 236 amino acids.
Protein length : 236
AA Sequence : VPAQVVLTPYKPEPGYECQISQEYY DRKAQMCCAKCPPGQYVKHFCNKTS DTVCADCEASMYTQVWNQFRTCLSC SSSCTTDQVEIRACTKQQNRVCACE AGRYCALKTHSGSCRQCMRLSKCGP GFGVASSRAPNGNVLCKACAPGTFS DTTSSTDVCRPHRICSILAIPGNAS TDAVCAPESPTLSAIPRTLYVSQPE PTRSQPLDQEPGPSQTPSILTSLGS TPIIEQSTKGG
Endotoxin : Less than 0.1 EU/µg of rMusTNF RII/TNFRSF1B as determined by LAL method.
Purity : >97% by SDS-PAGE and HPLC analyses.
Storage : Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution : We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 centigrade. Further dilutions should be made in appropriate buffered solutions.
Gene Name : Tnfrsf1b
Official Symbol : Tnfrsf1b
Synonyms : TNFRSF1B; tumor necrosis factor receptor superfamily, member 1b; tumor necrosis factor receptor superfamily member 1B; TNF-RII; TNFR-II; p75 TNFR; p80 TNF-alpha receptor; TNF receptor beta chain; tumor necrosis factor receptor 2; tumor necrosis factor receptor type II; p75; TNFBR; Tnfr2; CD120b; TNF-R2; TNFR80; TNFRII; Tnfr-1; TNF-R75; TNF-R-II; TNF-alphaR2; TNFalpha-R2;
Gene ID : 21938
mRNA Refseq : NM_011610
Protein Refseq : NP_035740
UniProt ID : P25119

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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