Recombinant Mouse Trak1 Protein, Myc/DDK-tagged

• Cat.No.: Trak1-6623M
• Product Overview: Purified recombinant protein of mouse full-length trafficking protein, kinesin binding 1 (Trak1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Involved in the regulation of endosome-to-lysosome trafficking, including endocytic trafficking of EGF-EGFR complexes and GABA-A receptors. Involved in mitochondrial motility. When O-glycosylated, abolishes mitochondrial motility. Crucial for recruiting OGT to the mitochondrial surface of neuronal processes. TRAK1 and RHOT form an essential protein complex that links KIF5 to mitochondria for light chain-independent, anterograde transport of mitochondria.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 104.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Trak1 trafficking protein, kinesin binding 1 [ Mus musculus (house mouse) ]
• Official Symbol: Trak1
• Synonyms: TRAK1; trafficking protein, kinesin binding 1; trafficking kinesin-binding protein 1; hyrt; AI413908; AI467545; mKIAA1042; 2310001H13Rik
• Gene ID: 67095
• mRNA Refseq: NM_175114
• Protein Refseq: NP_780323
• UniProt ID: Q6PD31