Recombinant Mouse Tyk2 protein(884-1174aa), His&Myc-tagged

• Cat.No.: Tyk2-7543M
• Product Overview: Recombinant Mouse Tyk2 protein(Q9R117)(884-1174aa), fused with N-terminal His tag and C-terminal Myc tag, was expressed in E.coli.

Specification

• Source: E.coli
• Species: Mouse
• Tag: N-His&C-Myc
• Protein length: 884-1174aa
• Form: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
• Molecular Mass: 41.2 kDa
• AASequence: SDPTVFHKRYLKKIRDLGEGHFGKV SLYCYDPTNDGTGEMVAVKALKEGC GPQLRSGWQREIEILRTLYHEHIVK YKGCCEDQGEKSVQLVMEYVPLGSL RDYLPRHCVGLAQLLLFAQQICEGM AYLHAQHYIHRDLAARNVLLDNDRL VKIGDFGLAKAVPEGHEYYRVREDG DSPVFWYAPECLKECKFYYASDVWS FGVTLYELLTYCDSNQSPHMKFTEL IGHTQGQMTVLRLTELLERGERLPR PDRCPCEIYHLMKNCWETEASFRPT FQNLVPILQTAQEKYQ
• Purity: Greater than 85% as determined by SDS-PAGE.
• Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C.

Gene Information

• Gene Name: Tyk2 tyrosine kinase 2 [ Mus musculus ]
• Official Symbol: Tyk2
• Synonyms: TYK2; tyrosine kinase 2; non-receptor tyrosine-protein kinase TYK2; tyrosine kinase TYK2; JTK1
• Gene ID: 54721
• mRNA Refseq: NM_001205312
• Protein Refseq: NP_001192241

Reviews

10/14/2022

Their expertise in protein production and purification ensures the delivery of a high-quality product that consistently performs well in my experiments.

06/15/2022

They are readily available to address any concerns or questions and supply valuable resources to assist in experimental design and optimization.

01/24/2018

Should I encounter any challenges or require technical assistance, the manufacturer provides prompt and knowledgeable support.

Q&As

Could TYK2 inhibitors have applications beyond autoimmune diseases?

Yes, TYK2 inhibitors might have potential in treating certain cancers and possibly other inflammatory conditions beyond autoimmune diseases.

What are the potential benefits of targeting TYK2 in treating autoimmune diseases?

TYK2 inhibition can potentially reduce inflammation and modulate immune responses without suppressing the entire immune system, unlike some other treatments.

Are there any clinical trials ongoing or completed regarding TYK2 inhibitors?

Yes, there are several clinical trials evaluating the efficacy and safety of TYK2 inhibitors in various autoimmune diseases.

How do TYK2 inhibitors differ from other treatments for autoimmune diseases?

TYK2 inhibitors are more targeted, aiming to interfere with specific signaling pathways involved in the immune response compared to broad immunosuppressants.

How are TYK2 inhibitors administered to patients?

Depending on the formulation, TYK2 inhibitors can be administered orally or through injections.