Recombinant Mouse Uba3 Protein, Myc/DDK-tagged


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Recombinant Mouse Uba3 Protein, Myc/DDK-tagged

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Cat.No. : Uba3-6766M
Product Overview : Purified recombinant protein of mouse full-length ubiquitin-like modifier activating enzyme 3 (Uba3), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
Description : The protein encoded by this gene is the catalytic subunit of the enzyme that activates NEDD8, a ubiquitin-like molecule that binds to its target proteins through an enzymatic reaction analagous to ubiquitylation. Embryonic mice deficient for this protein die prior to implantation and display apoptosis of the inner cell mass. Trophoblastic cells cannot enter S phase, demonstrating that this gene is required for cell cycle progression during embryogenesis. Two pseudogenes have been found for this gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2014]
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 49.2 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Uba3 ubiquitin-like modifier activating enzyme 3 [ Mus musculus (house mouse) ]
Official Symbol : Uba3
Synonyms : UBA3; ubiquitin-like modifier activating enzyme 3; NEDD8-activating enzyme E1 catalytic subunit; NEDD8-activating enzyme E1C; ubiquitin activating enzyme 3; ubiquitin-activating enzyme 3; ubiquitin-activating enzyme E1C; ubiquitin-like modifier-activating enzyme 3; Ube1c; AI256736; AI848246; AW546539; A830034N06Rik
Gene ID : 22200
mRNA Refseq : NM_011666
Protein Refseq : NP_035796
UniProt ID : Q8C878

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