Recombinant Mouse Vkorc1 Protein, Myc/DDK-tagged

• Cat.No.: Vkorc1-6925M
• Product Overview: Purified recombinant protein of Mouse vitamin K epoxide reductase complex, subunit 1 (Vkorc1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Vitamin K is essential for blood clotting but must be enzymatically activated. This enzymatically activated form of vitamin K is a reduced form required for the carboxylation of glutamic acid residues in some blood-clotting proteins. The product of this gene encodes the enzyme that is responsible for reducing vitamin K 2,3-epoxide to the enzymatically activated form. Fatal bleeding can be caused by vitamin K deficiency and by the vitamin K antagonist warfarin, and it is the product of this gene that is sensitive to warfarin. In humans, mutations in this gene can be associated with deficiencies in vitamin-K-dependent clotting factors and, in humans and rats, with warfarin resistance. [provided by RefSeq, Jul 2008]
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 17.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Vkorc1 vitamin K epoxide reductase complex, subunit 1 [ Mus musculus (house mouse) ]
• Official Symbol: Vkorc1
• Synonyms: VKORC1; vitamin K epoxide reductase complex, subunit 1; vitamin K epoxide reductase complex subunit 1; phylloquinone epoxide reductase; vitamin K1 2,3-epoxide reductase subunit 1; vitamin K1 epoxide reductase (warfarin-sensitive); D7Wsu86e
• Gene ID: 27973
• mRNA Refseq: NM_178600
• Protein Refseq: NP_848715
• UniProt ID: Q9CRC0