Recombinant Mouse Wdr1 Protein, Myc/DDK-tagged

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Recombinant Mouse Wdr1 Protein, Myc/DDK-tagged

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Cat.No. : Wdr1-6972M
Product Overview : Purified recombinant protein of Mouse WD repeat domain 1 (Wdr1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
Description : Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins. Enhances cofilin-mediated actin severing. Involved in cytokinesis. Involved in chemotactic cell migration by restricting lamellipodial membrane protrusions. Involved in myocardium sarcomere organization. Required for cardiomyocyte growth at the postnatal and maintenance at the adult stage. Involved in neutrophil actin dynamics and migration. Involved in megakaryocyte maturation and platelet shedding. Required for the establishment of planar cell polarity (PCP) during follicular epithelium development and for cell shape changes during PCP; the function seems to implicate cooperation with CFL1 and/or DSTN/ADF. Involved in the generation/maintenance of cortical tension. Involved in assembly and maintenance of epithelial apical cell junctions and plays a role in the organization of the perijunctional actomyosin belt.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 66.9 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Wdr1 WD repeat domain 1 [ Mus musculus (house mouse) ]
Official Symbol : Wdr1
Synonyms : WDR1; WD repeat domain 1; WD repeat-containing protein 1; WD40 repeat protein 1; actin-interacting protein 1; Aip1; rede; D5Wsu185e
Gene ID : 22388
mRNA Refseq : NM_011715
Protein Refseq : NP_035845
UniProt ID : O88342
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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