Recombinant Mouse Wdr83 Protein, Myc/DDK-tagged

Cat.No. : Wdr83-6988M
Product Overview : Purified recombinant protein of Mouse WD repeat domain containing 83 (Wdr83), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
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Description : Molecular scaffold protein for various multimeric protein complexes. Involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha via its interaction with EGLN3/PHD3. May promote degradation of HIF1A. May act by recruiting signaling complexes to a specific upstream activator. Also acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. At low concentrations it enhances ERK activation, whereas high concentrations lead to the inhibition of ERK activation. May also be involved in pre-mRNA splicing.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 34.4 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Wdr83 WD repeat domain containing 83 [ Mus musculus (house mouse) ]
Official Symbol : Wdr83
Synonyms : Wdr83; WD repeat domain containing 83; Mor; Morg1; 1500041N16Rik; WD repeat domain-containing protein 83; MAPK cascade scaffold protein; MAPK organizer 1; mitogen-activated protein kinase organizer 1
Gene ID : 67836
mRNA Refseq : NM_026399
Protein Refseq : NP_080675
UniProt ID : Q9DAJ4

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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