Recombinant Mouse Wee2 Protein, Myc/DDK-tagged
Cat.No. : | Wee2-6993M |
Product Overview : | Purified recombinant protein of Mouse WEE1 homolog 2 (S. pombe) (Wee2), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis during both prophase I and metaphase II. Required to maintain meiotic arrest in oocytes during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 62.2 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Wee2 WEE1 homolog 2 (S. pombe) [ Mus musculus (house mouse) ] |
Official Symbol : | Wee2 |
Synonyms : | Wee2; WEE1 homolog 2 (S. pombe); Wee1B; Gm1065; wee1-like protein kinase 2; mWee1B; wee1-like protein kinase 1B; wee1B kinase; EC 2.7.10.2 |
Gene ID : | 381759 |
mRNA Refseq : | NM_201370 |
Protein Refseq : | NP_958758 |
UniProt ID : | Q66JT0 |
Products Types
◆ Recombinant Protein | ||
WEE2-41H | Recombinant Active Human WEE2 Protein (Full length), N-GST-tagged | +Inquiry |
WEE2-0789H | Recombinant Human WEE2 Protein (D2-H567), Tag Free | +Inquiry |
WEE2-0790H | Recombinant Human WEE2 Protein (D2-H567), His/GST tagged | +Inquiry |
WEE2-365H | Recombinant Human WEE2 Protein, MYC/DDK-tagged | +Inquiry |
WEE2-10161M | Recombinant Mouse WEE2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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