Recombinant Mouse WRN Protein

• Cat.No.: WRN-18584M
• Product Overview: Recombinant Mouse WRN full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Mouse
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Wrn Werner syndrome homolog (human) [ Mus musculus ]
• Official Symbol: WRN
• Gene ID: 22427
• mRNA Refseq: NM_001122822.1
• Protein Refseq: NP_001116294.1
• UniProt ID: O09053

Reviews

10/15/2022

Supports our research with high-quality data.

03/15/2021

Reliable partner for our protein experiments.

04/03/2017

Helps us achieve research milestones consistently.

Q&As

How do genetic mutations in the WRN gene affect its function?

Mutations in WRN can disrupt its enzymatic activities, leading to genomic instability and disease.

What are the implications of altered WRN activity in aging and age-related diseases?

Altered WRN activity is associated with accelerated aging and increased risk of age-related diseases.

What role does WRN play in DNA repair and replication?

WRN plays a crucial role in both DNA repair and replication processes.

How does WRN deficiency lead to Werner syndrome?

Deficiency in WRN leads to accelerated aging symptoms in Werner syndrome, due to impaired DNA repair.

What potential therapeutic approaches target WRN for treating Werner syndrome and other age-related conditions?

Therapies targeting WRN aim to enhance DNA repair mechanisms, potentially treating Werner syndrome and related conditions.

How does WRN interact with other proteins in the maintenance of genomic stability?

WRN cooperates with other proteins to ensure accurate DNA repair and replication.

What is the primary function of WRN in cellular processes?

WRN is involved in DNA repair and maintenance of genomic stability.