Recombinant Mouse Yju2 Protein, Myc/DDK-tagged

• Cat.No.: Yju2-7034M
• Product Overview: Purified recombinant protein of Mouse YJU2 splicing factor (Yju2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. May protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 36 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Yju2 YJU2 splicing factor [ Mus musculus (house mouse) ]
• Official Symbol: Yju2
• Synonyms: Yju2; YJU2 splicing factor; Ccdc94; AI413813; 2900016D05Rik; splicing factor YJU2; YJU2 splicing factor homolog; coiled-coil domain containing 94; coiled-coil domain-containing protein 94
• Gene ID: 72886
• mRNA Refseq: NM_028381
• Protein Refseq: NP_082657
• UniProt ID: Q9D6J3