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Active Recombinant Pig IL6 protein

Cat.No. : IL6-1025P
Product Overview : Recombinant Pig IL6 protein(NP_999564.1)(Pro29-Met212) was expressed in E. coli.
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Source : E. coli
Species : Pig
Tag : N/A
Form : Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Bio-activity : 1. Measured by its binding ability in a functional ELISA. Immobilized sus scrofa (pig) IL6 at 2 μg/ml (100 μl/well) can bind Human IL-6R-His, the EC50 of Human IL-6R-His is 250-750 ng/mL. 2. Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is typically 1-5 ng/mL.
Molecular Mass : The recombinant sus scrofa IL6 consists 185 amino acids and predicts a molecular mass of 21.2 kDa.
Protein Length : Pro29-Met212
Purity : > 95 % as determined by SDS-PAGE.
Storage : Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : IL6 interleukin 6 (interferon, beta 2) [ Sus scrofa ]
Official Symbol : IL6
Synonyms : IL6; interleukin 6 (interferon, beta 2); interleukin-6; IL-6; interleukin-6 protein;
Gene ID : 399500
mRNA Refseq : NM_214399
Protein Refseq : NP_999564

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What is the dosage and usage of Il6? 07/15/2022

The dosage and usage of Il6 will vary according to the disease, and generally require individualized regulation by the physician according to the disease situation.

What are the pharmacokinetic properties of Il6? 06/16/2022

The pharmacokinetic characteristics of Il6 mainly include drug absorption, distribution, metabolism, excretion and other information.

Does Il6 have advantages in the treatment of multiple myeloma? 04/22/2022

Recombinant Il6 protein has a unique therapeutic advantage in the treatment of multiple myeloma. It can promote the proliferation and differentiation of hematopoietic stem cells and inhibit the growth of tumor cells.

Does Il6 have specific therapeutic effects for certain diseases? 05/27/2020

Il6 has specific therapeutic effects for certain diseases, such as rheumatoid arthritis, multiple myeloma and so on.

In which diseases is Il6 widely used? 11/20/2019

This protein is widely used in the treatment of rheumatoid arthritis, pneumonia, multiple myeloma, lymphoma, malignant tumors and other diseases.

What is the effect of Il6 on immune cells? 05/21/2019

The effects of Il6 on immune cells are mainly manifested as promoting cell proliferation and differentiation, regulating immune response, etc.

Customer Reviews (3)

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Reviews
03/05/2022

    Accurate localization and function within the cell.

    01/31/2021

      The binding affinity and affinity constant with the target are high.

      03/12/2020

        Can form a stable micellar structure.

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