Recombinant Pongo Abelii MTHFD1 Protein (1-305 aa), His-SUMO-tagged

• Cat.No.: MTHFD1-1869P
• Product Overview: Recombinant Pongo Abelii (Sumatran orangutan) (Pongo pygmaeus abelii) MTHFD1 Protein (1-305 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Research Area: Cell Biology. Protein Description: Partial.

Specification

• Description: 5,10-methylenetetrahydrofolate + NADP+ = 5,10-methenyltetrahydrofolate + NADPH. 5,10-methenyltetrahydrofolate + H2O = 10-formyltetrahydrofolate. ATP + formate + tetrahydrofolate = ADP + phosphate + 10-formyltetrahydrofolate.
• Source: E. coli
• Species: Pongo Abelii
• Tag: His-SUMO
• Form: Tris-based buffer,50% glycerol
• Molecular Mass: 49.0 kDa
• Protein length: 1-305 aa
• AA Sequence: MAPAEILNGREISAQIRARLKNQVT QLKEQVPGFTPGLAILLVGNRDDSN LYINVKLKAAEEIGIKATHIKLPRT TTESEVIKYITSLNEDSTVHGFLVQ LPLDSENSINTEEVINAIAPEKDVD GLTSISAGKLARGDLNDCFIPCTPK GCLELIKETGVPIAGRHAVVVGRSK IVGAPMHDLLLWNNATVTTCHSKTA NLDEEVNKGDILVVATGRPEMVKGE WIKPGAIVIDCGINYVPDDKKPNGR KVVGDVAYDEAKERASFITPVPGGV GPMTVAMLMQSTVESAKRFLEKFKP GKWMI
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA with reconstitution instruction is sent along with the products.

Gene Information

• Gene Name: MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 [ Pongo abelii (Sumatran orangutan) ]
• Official Symbol: MTHFD1
• Synonyms: MTHFD1; Short name:C1-THF synthase
• Gene ID: 100173036
• mRNA Refseq: NM_001132611
• Protein Refseq: NP_001126083
• UniProt ID: Q5R8P0